Another blog post sneaked out :X
TL;DR: Multiple password managers can help to ensure that you have the option to have very convenient integrations for passwords of low importance and an offline password manager for high-value passwords. Sometimes using just one is not enough. No password manager is perfect, sometimes you need more than one to cover all areas.
U2F offers the "high security" functionality you use "pass" for. Initially I was like "OMG I'm now going to switch all my authentication to U2F" but after a year I'm gradually moving to only use it for high-security websites. Simply because having to stick a physical device into computer is quite an usability obstacle to do it on every silly shopping session.
This is my personal microblog. It's filled with my fun, joy and silliness.